Primary Biliary Cholangitis Insights

This week's must-know community updates, latest research & events

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Top Stories

PPAR Agonists in PBC Care
PPAR agonists may help improve liver function for people with Primary Biliary Cholangitis who don't fully respond to standard treatments. They are being studied as a potential second-line option to enhance biochemical responses and manage symptoms.
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American Society of Gene & Cell Therapy’s Empowering Patients 2025 Summit Recap
Read why patients and caregivers are vital partners in research, clinical trial awareness empowers decision-making, regulators value patient voices, and addressing manufacturing hurdles is crucial for access.
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Golexanolone PBC trial delayed due to capsule issues
The trial for golexanolone, aimed at treating cognitive symptoms in PBC patients, has been delayed due to problems making the medication capsules, but it does not affect patient safety.
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Navigating Evolutions in PBC Care with Craig Lammert, MD
Dr. Lammert discusses changes in treating Primary Biliary Cholangitis, focusing on new therapies and uncertainties in care. His insights help manage the condition more effectively.
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Latest Research

A recent study by Tanaka et al. (2025) explores the use of E6011, an anti-human fractalkine monoclonal antibody, in treating primary biliary cholangitis (PBC). The study highlights the need for new treatments beyond the current first-line therapy, ursodeoxycholic acid (UDCA), due to the autoimmune nature of PBC.

The focus on developing new therapies like E6011 indicates a push towards more effective management options for PBC. While UDCA remains the standard treatment, there is a growing interest in exploring additional therapies to improve patient outcomes. This research suggests that there is ongoing effort to find better solutions for managing PBC, which could potentially lead to improved treatment options in the future.

Clinical Trials

Community News