Primary Biliary Cholangitis Insights

Ipsen's Iqirvo Accepted by SMC for PBC Treatment

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Latest Research

Research on Seladelpar in treating primary biliary cholangitis (PBC) highlights its potential as an alternative or complementary therapy to existing treatments like ursodeoxycholic acid and obeticholic acid. These medications are used to manage PBC by improving liver function and reducing bile buildup.

The focus on Seladelpar suggests an interest in exploring new treatment options for managing PBC symptoms and slowing disease progression. This study could provide insights into how Seladelpar compares to current therapies in terms of efficacy and patient outcomes, contributing to the search for effective treatments for PBC, a condition with limited therapeutic options beyond current medications and liver transplantation in advanced cases Study (2025).

Clinical Trials

This is a list of upcoming or ongoing clinical trials that are actively recruiting and have been listed or updated in the last two weeks:
A Study to Evaluate the Pharmacokinetics and Safety of K-808 (Pemafibrate) in Subjects With Primary Biliary Cholangitis With Compensated Cirrhosis and Without Cirrhosis.
Study Type
Phase I
Location
2 countries
Age Range
18+ Years
Enrollment
16
Seladelpar in Subjects With Primary Biliary Cholangitis (PBC) and Compensated Cirrhosis
Study Type
Phase III
Location
4 countries
Age Range
18+ Years
Enrollment
318
Global Prospective, Observational Cohort of Adult Patients With Primary Sclerosing Cholangitis (WIND-PSC Study)
Study Type
Observational
Location
3 countries
Age Range
18 - 75 Years
Enrollment
2000
A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment
Study Type
Observational
Location
6 countries
Age Range
0 - Not specified
Enrollment
424

Community News

PBC FoundationPBC FoundationApr 08, 2025

The assembled patient advocacy groups, clinicians, specialist nurses, specialist pharmacists, and industry partners, giving everything we have to make the PBC journey easier, smoother and with better results.

PBC Foundation Post
PBC FoundationPBC FoundationApr 08, 2025

Yesterday the Scottish Medicines Consortium (SMC) accepted Elafibranor for use in NHS Scotland.

Read the news article on our website, which also includes a link to the press release: https://www.pbcfoundation.international/new-treatments-for-pbc/

#pbc#PrimaryBiliaryCholangitis

PBC Foundation Post
PBC FoundationPBC FoundationApr 08, 2025

The PBC International Summit 2025 has now started, kicked off by Robert Mitchell-Thain's welcome message.

The Summit is a unique event taking place over four days during which stakeholders across PBC, including patient advocacy groups, clinicians, specialist nurses, specialist pharmacists, and industry partners, give everything we have to make the PBC journey easier, smoother and with better results.

Aspects that single out the Summit as something unique and special include:

🟣 The Summit has an itinerary but no agenda. The room decides where we go, what we focus on, how we get there.

🟣 The Summit is patient driven. 1 in 4 attendees is a patient or a patient advocate, ensuring that patients are part of every workgroup, every discussion, every single decision made in the room.

🟣 The floor has more power than the podium. Sure, whoever is at the podium is sharing thoughts, but the floor is where the real power lies, and the room itself carries more wisdom than the individual.

PBC Foundation Post